Is there a link between clindamycin and C difficile?
Receipt of clindamycin was associated with significantly increased likelihood for C difficile infection and receipt of gentamicin with significantly increased likelihood of acute kidney injury, although the absolute risk of these complications was low.
What are the side effects of clindamycin in women?
Primary outcomes were C difficile infection and acute kidney injury. C difficile infection was compared between women receiving clindamycin (with or without other antibiotics) and women receiving antibiotics other than clindamycin.
What happens to your microbiome when you get C diff?
A healthy microbiome helps protect you from infection, but antibiotics disrupt your microbiome, wiping out both the good and the bad bacteria. The effect of antibiotics can last as long as several months. If you come in contact with C. diff germs during this time, you can get sick.
Do you need treatment for C diff infection?
Colonization is more common than C. diff infection and does not require treatment. Because it’s possible to spread C. diff to others while you’re colonized, it’s important to always practice good hand hygiene, making sure to wash your hands well with soap and water before eating and after using the bathroom. Can I get C. diff in the hospital?
How many women have been diagnosed with Clostridium difficile?
Results: Of 5,657,523 women admitted for delivery hospitalization, 266,402 (4.7%) received clindamycin and 165,726 (2.9%) received gentamicin. C difficile infection was diagnosed in 0.04% of women receiving clindamycin.
Is it safe to take clindamycin hydrochloride for colitis?
“Because clindamycin hydrochloride therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate…” Clostridium difficile associated diarrhea ( CDAD) can indeed be deadly.