Welche Alternative gibt es zu Azathioprin?
Alternative remissionserhaltende Therapien zu Azathioprin sind Methotrexat (nur MC) sowie die Biologika Infliximab, Adalimumab, Ustekinumab (nur MC) und Golimumab (nur CU).
Wann schlägt Azathioprin an?
Wenn die Kortikoid-Therapie nicht ausreicht, wird gerne der Wirkstoff Azathioprin verordnet. Als Standardosis pro Tag gilt 2 mg pro kg Körpergewicht. Wichtig zu wissen dabei ist aber, dass die Wirkung erst nach etwa drei bis sechs Monaten einsetzt.
What are the reviews of azathioprine for ulcerative colitis?
Azathioprine has an average rating of 6.7 out of 10 from a total of 22 ratings for the treatment of Ulcerative Colitis. 55% of reviewers reported a positive effect, while 23% reported a negative effect. Imuran (azathioprine): “Have had ulcerative colitis for 26 years.
When was azathioprine first used to treat IBD?
In general azathioprine is not one of the first medications used by IBD patients when they are first diagnosed. It has been used by people with Crohn’s disease and ulcerative colitis since the 1960s and is thought to be prescribed to around 1 in 5 patients with IBD. What is azathioprine?
How does azathioprine work on the immune system?
Azathioprine reduces the number of white blood cells in the body – the immune system relies on these white blood cells and by reducing them it interrupts the immune system’s function. It is chemically very similar to mercaptopurine, although azathioprine is used more often in IBD.
How long does it take azathioprine to take effect?
It is a slow-acting drug and can take 3-6 months before any effect is noticed. People are sometimes given azathioprine if they are having difficulty coming off of corticosteroids or as a follow-on from steroids. This allows the dose of steroids to be reduced as the azathioprine takes effect.