Was machen die Odontoblasten?
Odontoblasten sitzen am Rand des Zahnmarks direkt an der Grenze zur Zahnbeinschicht. Sie sind mit freien Nervenenden verbunden und daher mitverantwortlich für die Schmerzempfindlichkeit der Zähne. Ihre Hauptaufgabe ist die Bildung von Dentin (Substantia eburnea).
Sind im Dentin Nerven?
Er ist die härteste Substanz im menschlichen Körper. Darunter liegt das Zahnbein (Dentin), das wiederum das Zahnmark (Pulpa) umschließt. Es ist mit Nerven durchzogen und wird durch Blutgefäße versorgt. Von hier aus reichen auch Kanälchen ins Dentin, die Nervenzellfortsätze enthalten.
Wie heißt die Flüssigkeit in den dentinkanälchen?
[1] In den Dentinkanälchen befindet sich der Dentinliquor.
What is the function of the odontoblast?
Odontoblasts are the only cells that secrete dentine and if they die, the formation of a dentine bridge is still possible, providing that new odontoblast-like cells differentiate in the area. Hong Zhang, Jan C.-C. Hu, in Reference Module in Biomedical Sciences, 2018
What is the difference between odontoblast and secretory odontoblasts?
During odontoblast differentiation, the short, columnar-shaped pre-odontoblasts elongate and extend cellular processes toward the basement membrane where dental epithelium and ecto-mesenchyme interface. Secretory odontoblasts are fully differentiated polarized columnar cells containing numerous organelles in their supranuclear area.
Can odontoblasts sense heat and cold?
Odontoblasts can also sense noxious stimuli such as cold, heat, mechanical stress, etc. Several lines of evidence have demonstrated that odontoblasts express mechano- and/or thermosensitive transient receptor potential ion channels that are likely to sense heat and/or cold or movements of dentinal fluid within tubules.
What is autophagy in odontoblast and why is it important?
Autophagy in odontoblast is important for reducing and rearranging the organelles as the odontoblasts transition from secretory to aged cells. Once the primary dentin is formed, the production of the secondary dentin is slower and persists throughout the lifetime of the tooth ( Couve, 1986) ( Fig. 2 ).