War Contergan Schlafmittel?
Mit dem Namen Contergan ist einer der größten Arzneimittel-Skandale verbunden. Das Schlafmittel, welches auch bei Schwangerschaftsübelkeit eingenommen wurde, verursachte Missbildungen bei Neugeborenen.
Wann war das mit Contergan?
Anfang November 1961 fand Lenz, wonach er suchte. In allen Fällen hatten die werdenden Mütter während der Schwangerschaft ein neuartiges, 1954 von der Aachener Pharmafirma Grünenthal synthetisiertes und seit 1957 angebotenes Schlafmittel zu sich genommen: Contergan.
Is thalidomide still used in the United States?
Unfortunately, the stereochemistry of thalidomide and its profound effect on the human body was not realized in the 1950s and 1960s when the drug was prescribed to many pregnant women. Although the thalidomide disaster had a widespread impact in Europe, thalidomide’s effects were not as prevalent in the United States.
What was the thalidomide disaster in Germany?
THE THALIDOMIDE Disaster in Germany In November 1961, German citizens were shocked to learn about thousands of babies born with severe birth defects in their country. Most of the babies were born with deformities of the arms and/or legs (phocomelia).
What is the true story of thalidomide distribution?
The true story of thalidomide distribution in the United States was buried in FDA documents and a Library of Congress archive for decades. A reconstruction of the events of 1956-1965 is now possible thanks to the tireless efforts of several people who sought to uncover the truth.
What are enantiomers of thalidomide?
This is where the concept of enantiomers comes in. The thalidomide molecule occurs naturally in two forms, (R)- thalidomide and (S)- thalidomide, which are enantiomers, or mirror image molecules, of each other. The (R)-form has remedial properties, while the (S)-form is a teratogen, an agent that can cause birth defects.
https://www.youtube.com/watch?v=nc3nHrDEWs4