Was ist ein B Virus?
Die Hepatitis B ist eine meldepflichtige Viruserkrankung, die mit einer Leberentzündung einhergeht. Eine akute Infektion kann in eine chronische Verlaufsform übergehen. Die Viren werden vor allem über ungeschützten Geschlechtsverkehr bzw. Blut übertragen.
Wie erkenne ich ob ich Hepatitis habe?
Mögliche Anzeichen und Folgen von Hepatitis A
- Abgeschlagenheit.
- Appetitlosigkeit.
- Kopf-, Muskel- und Gelenkschmerzen.
- Übelkeit, Erbrechen, Bauchschmerzen.
- Fieber.
- Abneigung gegen Fett und Alkohol.
What kind of liver disease does HBV cause?
HBV infection leads to a wide spectrum of liver disease ranging from acute hepatitis (including fulminant hepatic failure) to chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC).2The diagnosis of HBV infection and its associated disease is based on a constellation of clinical, biochemical]
How does HBV reactivate in the human body?
HBV reactivation is the abrupt reappearance or rise in HBV DNA in a patient with previously inactive chronic or resolved hepatitis B. It is often accompanied by a flare in disease activity with elevation of liver enzymes with or without symptoms. HBV reactivation can be severe, resulting in death (13).
How does the HBV virus replicate in the host?
HBV replicates through an RNA intermediate and can integrate into the host genome. The unique features of the HBV replication cycle confer a distinct ability of the virus to persist in infected cells.
Are there signs and symptoms of acute HBV infection?
Not all people with acute HBV infection have symptoms. The presence of signs and symptoms varies by age. Most children <5 years of age and newly infected immunosuppressed adults are generally asymptomatic, whereas 30%–50% of people age ≥5 years have signs and symptoms ( 6 ). When present, signs and symptoms of acute HBV infections can include