Welche Antibiose bei Helicobacter pylori?
Mit einer Eradikationstherapie lässt sich Helicobacter pylori in der Regel erfolgreich bekämpfen. Standard ist eine Tripeltherapie aus zwei Antibiotika und einem Protonenpumpeninhibitor – entweder das französische Tripleschema mit Amoxicillin und Clarithromycin oder das italienische mit Metronidazol und Clarithromycin.
Welche Medikamente helfen bei Helicobacter?
Helicobacter-Eradikation Dabei gibt es mehrere Möglichkeiten: Für 7 bis 14 Tage die beiden Antibiotika Clarithromycin und Metronidazol, plus einen Protonenpumpenhemmer wie Omeprazol oder Pantoprazol. Für 7 bis 14 Tage die Antibiotika Clarithromycin und Amoxicillin, plus einen Säurehemmer.
Is there a cure for Helicobacter pylori with levofloxacin?
The eradication rate achieved by a levofloxacin-based re-treatment seems to be decreasing, and its efficacy is reduced in presence of levofloxacin resistance. 1. Introduction Standard triple therapies fail to cure Helicobacter pylori infection in more than 20–30% of patients [1], [2].
Which is the second line treatment for Helicobacter pylori?
First-line Helicobacter pylori therapy fails in more than 20% of patients. Quadruple therapy is the suggested second-line therapy, but bismuth salts are not anymore available worldwide. This study aimed to assess the efficacy of a levofloxacin–amoxycillin triple therapy as a second-line treatment, and the role of primary levofloxacin resistance.
What was the eradication rate of H.pylori?
H. pylori infection was eradicated in 24 patients, accounting for a 72.7% (95% CI: 57–88) eradication rate at both intention-to-treat and per protocol analyses. The eradication rate was higher in patients harbouring levofloxacin-susceptible than resistant strains (75% versus 33.3%; P = 0.074).
Is there a second line for levofloxacin?
The efficacy of this regimen remains stable with time. Ten-day levofloxacin-containing therapy is an encouraging second-line strategy, providing a safe and simple alternative to quadruple therapy in patients whose previous standard triple therapy has failed. The efficacy of this regimen remains stable with time.