Welche Blutgruppe ist HH?
Patienten mit der Hh-Antigen-Blutgruppe Bombay hingegen haben Antikörper gegen alle roten Blutkörperchen (Erythrozyten) der Blutgruppen A, B, AB und 0. Sie können nur Spenderblut (oder Eigenblut) mit Erythrozyten der Blutgruppe Bombay (0h) erhalten, da es sonst zu lebensbedrohlichen Komplikationen kommen kann.
Welche Blutgruppe kommt am häufigsten vor?
37 Prozent der Menschen in Deutschland haben die Blutgruppe „A+“. Etwa 35 Prozent tragen die Blutgruppe „0+“. Die Blutgruppe „B+“ kommt bei 9 Prozent der Menschen in Deutschland vor, die Blutgruppe „A-“ und „0-“ bei jeweils 6 Prozent.
Is the Bombay blood group an O blood group?
The Bombay anti-H is active over a wide thermal range. It is an IgM antibody that can bind complement and cause red cell lysis. Because the H Ag is common to all ABO blood group, Bombay blood is incompatible with all ABO donors. In routine forward grouping, using anti-A, anti-B, and anti-AB. The Bombay would phenotype as an O blood group.
Is there a risk of misinterpreting Bombay blood group?
As because in our country there is routine practice of „only forward or cell type grouping“ using finger prick method by voluntary blood donors organization and various blood banks; so there is tremendous chance of misinterpretation or unexploration of this Bombay blood group.
How are Bombay cells converted to Group A or B?
A and B genes code for enzymes that add an immunodominant sugar to the H antigen. Bombay cells cannot be converted to group A or B by the specific transferases. This supports the concept that the H structure serves as the acceptor molecule or precursor substance for the product of the A or B gene -specified transferases.
Which is a rare allele in the Bombay blood group?
It is very common 99.9% of all individuals have an HH or Hh genotype. The allele h is very rare and does not produce the L-Fucose transferase necessary for the formation of the H-Structure. The genotype (hh) or H null is extremely rare and is known as the Bombay Phenotype or O h.